Wu Yao Selected Research

Silicosis

4/2024	FOXF1 reverses lung fibroblasts transdifferentiation via inhibiting TGF-β/SMAD2/3 pathway in silica-induced pulmonary fibrosis.
4/2024	Bioinformatics-based dynamics of cuproptosis -related indicators in experimental silicosis.
3/2024	Exposure to micron-grade silica particles triggers pulmonary fibrosis through cell-to-cell delivery of exosomal miR-107.
3/2024	Corrigendum to "A2aR inhibits fibrosis and the EMT process in silicosis by regulating Wnt/β-catenin pathway" [Ecotoxicol. Environ. Saf. 249 (2023) 114410].
11/2023	Silica-exposed macrophages-secreted exosomal miR125a-5p induces Th1/Th2 and Treg/Th17 cell imbalance and promotes fibroblast transdifferentiation.
8/2023	Dynamics of the inhibitory immune checkpoint TIM-3 in mouse pulmonary phagocytes after silica exposure.
1/2023	Mitochondrial folate pathway regulates myofibroblast differentiation and silica-induced pulmonary fibrosis.
1/2023	A2aR inhibits fibrosis and the EMT process in silicosis by regulating Wnt/β-catenin pathway.
1/2023	Exosomal miR-125a-5p regulates T lymphocyte subsets to promote silica-induced pulmonary fibrosis by targeting TRAF6.
1/2023	MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.

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Wu Yao Research Topics

Disease

28	Silicosis 04/2024 - 09/2006
18	Pulmonary Fibrosis (Fibrosing Alveolitis) 04/2024 - 07/2018
15	Neoplasms (Cancer) 12/2023 - 11/2013
11	Fibrosis (Cirrhosis) 04/2024 - 01/2017
10	Pneumoconiosis 01/2023 - 07/2005
7	Lung Neoplasms (Lung Cancer) 01/2023 - 05/2012
6	Inflammation (Inflammations) 06/2021 - 01/2017
5	Lung Diseases (Lung Disease) 03/2024 - 04/2020
4	Pneumonia (Pneumonitis) 09/2023 - 04/2014
4	Carcinogenesis 01/2019 - 01/2014
3	Adenocarcinoma of Lung 01/2023 - 11/2018
3	Neoplasm Metastasis (Metastasis) 01/2023 - 01/2014
2	Idiopathic Pulmonary Fibrosis 09/2023 - 11/2020
2	Occupational Diseases (Occupational Disease) 01/2023 - 06/2021
2	Lung Injury 08/2022 - 01/2022
2	Chromosomal Instability (Chromosome Stability) 08/2017 - 01/2016
2	Anthracosis 09/2014 - 07/2005
1	Communicable Diseases (Infectious Diseases) 06/2023
1	Type 2 Diabetes Mellitus (MODY) 06/2023
1	Stomach Ulcer (Gastric Ulcer) 09/2022
1	Body Weight (Weight, Body) 08/2022
1	Colorectal Neoplasms (Colorectal Cancer) 07/2022
1	Microsatellite Instability 07/2022
1	Prostatic Neoplasms (Prostate Cancer) 01/2022
1	Acquired Immunodeficiency Syndrome (AIDS) 10/2021
1	Hyperlipidemias (Hyperlipidemia) 01/2021
1	Bites and Stings (Sting) 05/2020

Drug/Important Bio-Agent (IBA)

24	Silicon Dioxide (Silica)FDA LinkGeneric 04/2024 - 09/2017
13	Proteins (Proteins, Gene)FDA Link 12/2023 - 09/2010
12	MicroRNAs (MicroRNA)IBA 11/2023 - 01/2018
6	CytokinesIBA 11/2023 - 07/2005
5	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 09/2023 - 05/2010
5	Biomarkers (Surrogate Marker)IBA 01/2020 - 09/2012
5	Coal (Coals)IBA 09/2014 - 07/2005
3	Transcription Factors (Transcription Factor)IBA 04/2024 - 12/2020
3	Messenger RNA (mRNA)IBA 08/2023 - 09/2010
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2020 - 06/2011
3	Transforming Growth Factor beta1 (TGF beta 1)IBA 09/2006 - 07/2005
2	CateninsIBA 03/2024 - 01/2023
2	TNF Receptor-Associated Factor 6 (TRAF6)IBA 11/2023 - 01/2023
2	Bleomycin (Blenoxane)FDA LinkGeneric 09/2023 - 09/2023
2	geranylgeranylacetone (teprenone)IBA 09/2023 - 09/2023
2	Metformin (Glucophage)FDA LinkGeneric 06/2023 - 08/2022
2	Glucose (Dextrose)FDA LinkGeneric 06/2023 - 09/2012
2	Connective Tissue Growth FactorIBA 01/2023 - 01/2021
2	Nuclear Proteins (Protein, Nuclear)IBA 01/2023 - 01/2022
2	HMGB1 Protein (HMG1)IBA 01/2023 - 01/2022
2	Benzo(a)pyreneIBA 01/2023 - 01/2019
2	Folic Acid (Vitamin M)FDA LinkGeneric 01/2023 - 11/2020
2	Phosphatidylcholines (Phosphatidylcholine)IBA 11/2022 - 01/2021
2	Long Noncoding RNAIBA 05/2022 - 01/2022
2	Telomerase (Telomerase Reverse Transcriptase)IBA 10/2021 - 09/2017
2	Transforming Growth Factors (Transforming Growth Factor)IBA 03/2021 - 01/2021
2	CokeIBA 10/2020 - 05/2020
2	Zinc Oxide FDA Link 01/2018 - 04/2014
2	Coal Tar (Estar)IBA 08/2017 - 01/2014
2	Interleukin-8 (Interleukin 8)IBA 12/2016 - 04/2014
2	EnzymesIBA 09/2012 - 09/2006
2	ImmunosorbentsIBA 09/2012 - 09/2006
1	IonsIBA 04/2024
1	Ceruloplasmin (Ferroxidase)IBA 04/2024
1	CopperIBA 04/2024
1	6-methyladenineIBA 12/2023
1	N-methyladenosineIBA 12/2023
1	Interleukin-17 (Interleukin 17)IBA 11/2023
1	Interleukin-4 (Interleukin 4)IBA 11/2023
1	CollagenIBA 09/2023
1	Hepatitis A Virus Cellular Receptor 2IBA 08/2023
1	Lactic Acid (Lactate)FDA LinkGeneric 06/2023
1	Blood Glucose (Blood Sugar)IBA 06/2023
1	Benzene (Benzole)IBA 02/2023
1	4- methoxy- 8- (ribofuranosylamino)pyrimido(5,4- d)pyrimidineIBA 01/2023
1	tricaprylinIBA 01/2023
1	InflammasomesIBA 01/2023
1	Histones (Histone)IBA 01/2023
1	1-Acylglycerophosphocholine O-Acyltransferase (1 Acylglycerophosphocholine O Acyltransferase)IBA 11/2022
1	LipidsIBA 11/2022
1	Lysophosphatidylcholines (Lysophosphatidylcholine)IBA 11/2022
1	Cimetidine (Biomet)FDA LinkGeneric 09/2022
1	AMP-Activated Protein KinasesIBA 08/2022
1	B7-H1 AntigenIBA 07/2022
1	Immune Checkpoint InhibitorsIBA 04/2022
1	Untranslated RNA (Noncoding RNA)IBA 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	Glycyrrhizic Acid (Glycyrrhizin)IBA 01/2022
1	Hydroxyproline (4 Hydroxyproline)IBA 06/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2021
1	diacetyldichlorofluoresceinIBA 03/2021
1	NADP (NADPH)IBA 03/2021
1	Glycerophospholipids (Phosphoglycerides)IBA 01/2021
1	Platelet-Derived Growth FactorIBA 01/2021
1	ginsenoside Rb1IBA 01/2021
1	CholesterolIBA 01/2021
1	Liver X ReceptorsIBA 12/2020
1	Interleukin-10 (Interleukin 10)IBA 04/2020
1	Interleukin-6 (Interleukin 6)IBA 04/2020
1	InterleukinsIBA 04/2020

Therapy/Procedure

2	Immunotherapy 01/2023 - 07/2022
1	Precision Medicine 06/2023
1	Intraperitoneal Injections 08/2022